![]() Michael Dreher received speaker fees from Actelion, Astra Zeneca, Bayer, Berlin Chemie, Boehringer, Chiesi, GSK, Janssen-Cilag, Hamilton, Heinen und Lö wenstein, Intermune, Linde, Novartis, Pfizer, Philips Respironics, ResMed, Roche, Weinmann consulting fees from Almirall, Astra Zeneca, Boehringer, Chiesi, GSK, Hamilton, Janssen-Cilag, Linde, Novartis, Pfizer, Philips Respironics, ResMed and Roche and research grants from Linde, Philips Respironics and ResMed. Tomotaka Kawayama received grants from Novartis and lecture fees from AstraZeneca, GlaxoSmithKline (GSK), Boehringer Ingelheim, Novartis, Teijin Home Healthcare, Sanofi, Kyorin and MeijiSaika Pharma. Marc Miravitlles has received speaker fees from AstraZeneca, Boehringer Ingelheim, Chiesi, Cipla, Menarini, Rovi, Bial, Kamada, Sandoz, Zambon, CSL Behring, Grifols and Novartis consulting fees from AstraZeneca, Atriva Therapeutics, Boehringer Ingelheim, Chiesi, GlaxoSmithKline, Bial, Gebro Pharma, CSL Behring, Inhibrx, Laboratorios Esteve, Ferrer, Mereo Biopharma, Verona Pharma, Spin Therapeutics, ONO Pharma, pH Pharma, Palobiofarma SL, Takeda, Novartis, Sanofi and Grifols and research grants from Grifols. This article reviews global and regional/national guideline recommendations for the use of LABA/LAMA in COPD, examines the evidence for the effectiveness and safety of LABA/LAMA versus other therapies and offers a practical guide for clinicians to help ensure appropriate use of LABA/LAMA therapy.ĬOPD LABA/LAMA bronchodilator inhaled corticosteroid. ![]() However, despite consistent guideline recommendations, real-world prescribing data indicate that LAMA and/or LABA without an inhaled corticosteroid are not the most widely prescribed therapies in COPD. The recommendations for LABA/LAMA are broader in the American Thoracic Society treatment guidelines, which strongly recommend LABA/LAMA combination therapy over LAMA or LABA monotherapy in patients with COPD and dyspnea or exercise intolerance. The Global Initiative for Chronic Obstructive Lung Disease 2022 report recommends initial pharmacological treatment with a long-acting muscarinic antagonist (LAMA) or a long-acting β 2-agonist (LABA) as monotherapy for most patients, or dual bronchodilator therapy (LABA/LAMA) in patients with more severe symptoms, regardless of exacerbation history. Inhaled bronchodilators (alone or in combination) are the cornerstone of treatment for symptomatic patients with COPD, either as initial/first-line treatment or for second-line/treatment escalation in patients who experience persistent symptoms or exacerbations on monotherapy.
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![]() In addition to her 15 years of leading clinical and consumer testing in the GH Institute Beauty Lab, she has R&D experience through her seven-year stint at Unilever U.S. ![]() He also independently reviews new products in the wellness space for Good Housekeeping, which he has done previously for Martha Stewart Living and Cooking Light.įor this story, Zee worked closely with Birnur Aral, Ph.D. In his role as Health Editor, Zee Krstic works hand in hand with analysts in the Good Housekeeping Institute to highlight consumer-facing input from leading health experts he interweaves doctors' and healthcare providers' expertise into shopping guides to better educate readers. 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But there are additional concerns when you're applying a product to the skin of babies and growing children, especially if you've been worried about headlines from the last few years around sunscreen safety. Our skincare experts have established optimal sunscreens for sensitive skin as well as products made with entirely natural formulas. But even that can be tricky, as every child may have different reactions to certain ingredients, consistencies or application methods. Finding the best sunscreen for kids and babies should be the easy part. Slathering sunscreen on a squirmy baby or a kid who'd rather be romping in the waves than standing still long enough for you to cover all their exposed skin is a challenge in itself. ![]() ![]() Regardless of how many carbs your beer does have, we must not forget about its alcohol content and what the alcohol does to the body. Unfortunately, these additional ingredients also add more calories and carbs to the beer as well, making them even worse for you from a health and dieting perspective. On top of that, some beer brewers add other ingredients like unmalted grains and added sugars to add to the flavor and drinkability of the beer. The hops and yeast contribute a tiny amount of calories, but calorie content of the beer depends mostly on the grains. They are the primary source of calories and carbs that you get from the beer. There is one problem with these grains, however. Other malted grains commonly used in brewing include wheat, rye and oats. Malted barley is by far the most widely used grain in beer making, but it is not the only one. The malted grains are also the primary source of color, body, flavor, and aroma in beer. The yeast will then digest these simple sugars even further to create alcohol. Side note: malted grains are grains that are germinated and dried in order to activate enzymes that help break down the starch from the grains into simple sugars. However, not all of the sugars and carbohydrates from the grain will be fermented, providing the beer with a combination of carbonation, alcohol, and carbs that beer drinkers love. The malted grains are the meat and potatoes of beer, and the reason why beer is sometimes called “liquid bread.” They provide the sugars that are fermented by yeast to produce alcohol and CO2 (natural carbonation). ![]() What is Beer Made Of? The First Clue as to Why Most Beers Aren’t Keto-FriendlyĪlmost every beer consists of four main ingredients: water, malted grains, hops, and yeast. If you’d like to skip ahead, click to see the full low-carb and keto beer list > But before we talk about these keto-friendly beers and other low-carb beer alternatives, let’s get a better understanding of why beer can make it much harder for you to have the body and health that you’ve always wanted. There are dozens of beers that have low enough calories and carbs that they can be consumed while you are on a ketogenic diet or a low carb diet. Their carb count is typically so high that just one beer will take a good chunk out of your carb limit for the day.įortunately, this isn’t the case for every beer. What’s even worse is that most beers are not even close to being keto or low-carb friendly. This is because the average beer has around 150 or more calories in every 12-ounce serving along with a dose of alcohol, which will cause several adverse effects throughout the body when you have too much. However, that beer that you love so much may not be helping you at all in the long run. 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In the 1950s, a few women appeared on the cover of Sports Illustrated, but the 1964 issue is considered to be the beginning of the current format known as the Swimsuit Issue. Campbell soon became a powerful figure in modeling and molded the issue into a media phenomenon by featuring "bigger and healthier" California women and printing the names of the models with their photos, beginning a new supermodel era. The first issue, released in 1964, entailed a cover featuring Babette March and a five-page layout. He asked fashion reporter Jule Campbell to go on a shoot to fill space, including the cover, with a beautiful model. The swimsuit issue was invented by Sports Illustrated editor Andre Laguerre to fill the winter months, a typically slow point in the sporting calendar. Since 1964, the issue had been published every February, but starting in 2019, the issue was made available in May. 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